Article
Influence of Single Nucleotide Polymorphisms on CRS Outcomes: A Preliminary Observational Study.
The Laryngoscope - 1 Feb 2025
Maniaci Antonino, Bonacci Paolo, Stefani Stefania, Cocuzza Salvatore, Merlino Federico, Saibene Alberto Maria, Sangiorgio Giuseppe, Maza-Solano Juan, Lechien Jerome R, La Mantia Ignazio, Musso Nicolo'
Abstract excerpt
OBJECTIVE(S): To conduct a preliminary investigation into the relationship between specific SNP variants, type II inflammation, and the effectiveness of dupilumab therapy and surgery in patients with CRS. METHODS: In this prospective study, 48 subjects were enrolled, comprising 32 CRS patients and 16 healthy controls. The CRS patients were subjected to either dupilumab therapy or endoscopic surgery according to...
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