Article
MHC class I chain-related gene A transmembrane polymorphism in Spanish women with breast cancer.
Tissue antigens - 1 Jul 2009
Lavado-Valenzuela R, Benavides M, Carabantes F, Alonso A, Caballero A
Abstract excerpt
The NKG2D-major histocompatibility complex class I-related chain A (MICA) system plays a key role in the antitumoral immune response. We studied five alleles of a microsatellite in the MICA transmembrane region; one of which (MICA-A5.1) gives rise to a truncated protein. The MICA-A5 allele was reduced in breast cancer patients compared with healthy controls (P = 0.04). Given the association between the HLA-B7...
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