Article
The HLA-B7 allele confers susceptibility to breast cancer in Spanish women.
Immunology letters - 15 Nov 2005
Lavado Rocio, Benavides Manuel, Villar Esther, Ales Inmaculada, Alonso Antonio, Caballero Abelardo
Abstract excerpt
BACKGROUND: Several HLA alleles are associated with susceptibility or protection in breast cancer. The particular allele varies depending on the geographical region. A study in a small group of Spanish patients using serological methods found an association with HLA-B7. We undertook a larger study in southern Spain using molecular biology techniques. METHODS: Genotype variants of HLA class I and II were typed by...
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