Article
MHC class I chain-related gene a diversity in patients with cutaneous malignant melanoma from southeastern Spain.
Disease markers - 1 Jan 2015
Campillo José Antonio, López-Hernández Ruth, Martínez-Banaclocha Helios, Bolarín José Miguel, Gimeno Lourdes, Mrowiec Anna, López Manuela, Las Heras Beatriz, Minguela Alfredo, Moya-Quiles Maria Rosa, Legáz Isabel, Frías-Iniesta José Francisco, García-Alonso Ana María, Álvarez-López María Rocío, Martínez-Escribano Jorge Antonio, Muro Manuel
Abstract excerpt
A limited number of studies have been performed so far on the polymorphism in the transmembrane region (exon 5) of the major histocompatibility complex class I chain-related gene A (MICA) in patients with melanoma. However, the influence of MICA polymorphism in extracellular domains (exons 2, 3, and 4) has not been investigated on melanoma disease. This study aims to characterize the influence of extracellular...
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