Article
MIC-A polymorphism in Japanese and a MIC-A-MIC-B null haplotype.
Immunogenetics - 1 Jul 1999
Komatsu-Wakui M, Tokunaga K, Ishikawa Y, Kashiwase K, Moriyama S, Tsuchiya N, Ando H, Shiina T, Geraghty D E, Inoko H, Juji T
Abstract excerpt
A polymorphic gene, MIC-A, is one of the MIC family of genes which is composed of a group of homologous genes interspersed in the class III and class I regions of the major histocompatibility complex. MIC-A is located 46 kilobases (kb) centromeric of HLA-B, and is preferentially expressed in the epithelial cells and intestinal mucosa. Recently, MIC-A and the closely related MIC-B were reported as the molecules...
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