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Article

Role of beta-defensin-1 polymorphisms in mother-to-child transmission of HIV-1.

Journal of acquired immune deficiency syndromes (1999) - 1 May 2009

Ricci Elisabetta, Malacrida Sandro, Zanchetta Marisa, Montagna Marco, Giaquinto Carlo, De Rossi Anita

Abstract excerpt

BACKGROUND AND OBJECTIVES: Mother-to-child transmission (MTCT) of HIV-1, the main source of pediatric AIDS, is multifactorial. Defensins provide microbial barriers and function as effectors of innate immunity. This study investigated the relationship between genetic variants of beta-defensin-1 gene and MTCT of HIV-1. PATIENTS AND METHODS: Three hundred children, 118 HIV-1 infected and 182 HIV-1 uninfected, born...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Immunity, Innate

Share to Infectious Disease Transmission, Vertical

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Source

Identifiers

PMID: 19390326
DOI: 10.1097/QAI.0b013e31819df249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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