Article
DEFB-1 genetic polymorphism screening in HIV-1 positive pregnant women and their children.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Jan 2006
Segat Ludovica, Milanese Michele, Boniotto Michele, Crovella Sergio, Bernardon Maria, Costantini Monica, Alberico Salvatore
Abstract excerpt
OBJECTIVE: In our study we evaluated the frequency of three SNPs (-52 G/A, -44 C/G; -20 G/A) in the 5' UTR of DEFB-1 gene, in a cohort of 130 HIV-1 infected mothers and their children, collected by the Italian group SIGO in Obstetrics and Gynecology. METHODS: The three SNPs (-52 G/A, -44 C/G; -20 G/A) in the 5' UTR of DEFB-1 gene were genotyped by direct sequencing of PCR products. RESULTS: The C allele at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.