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Article

A role for ubiquitin in the clearance of nonfunctional rRNAs.

Genes & development - 15 Apr 2009

Fujii Kotaro, Kitabatake Makoto, Sakata Tomoko, Miyata Atsumi, Ohno Mutsuhito

Abstract excerpt

Quality control mechanisms operate in various steps of ribosomal biogenesis to ensure the production of functional ribosome particles. It was reported previously that mature ribosome particles containing nonfunctional mutant rRNAs are also recognized and selectively removed by a cellular quality control system (nonfunctional rRNA decay [NRD]). Here, we show that the NRD of 25S rRNA requires a ubiquitin E3 ligase...

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Identifiers

PMID: 19390089
DOI: 10.1101/gad.1775609
PMCID: PMC2675866

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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