Article
The effect of varying analytical methods on estimates of anti-malarial clinical efficacy.
Malaria journal - 22 Apr 2009
Verret Wendy J, Dorsey Grant, Nosten Francois, Price Ric N
Abstract excerpt
BACKGROUND: Analytical approaches for the interpretation of anti-malarial clinical trials vary considerably. The aim of this study was to quantify the magnitude of the differences between efficacy estimates derived from these approaches and identify the factors underlying these differences. METHODS: Data from studies conducted in Africa and Thailand were compiled and the risk estimates of treatment failure,...
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