Article
The use of genotyping in antimalarial clinical trials: a systematic review of published studies from 1995-2005.
Malaria journal - 14 Dec 2006
Collins William J, Greenhouse Bryan, Rosenthal Philip J, Dorsey Grant
Abstract excerpt
BACKGROUND: The use of genotyping to distinguish recrudescent from new infections is currently recommended for all clinical antimalarial efficacy trials by the World Health Organization. However, genotyping-adjusted drug efficacy estimates may vary between trials due to the use of different genotyping methods and to the different settings in which these methods are applied. METHODS: A systematic review of all...
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