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Article

Gel versus capillary electrophoresis genotyping for categorizing treatment outcomes in two anti-malarial trials in Uganda.

Malaria journal - 15 Jan 2010

Gupta Vinay, Dorsey Grant, Hubbard Alan E, Rosenthal Philip J, Greenhouse Bryan

Abstract excerpt

BACKGROUND: Molecular genotyping is performed in anti-malarial trials to determine whether recurrent parasitaemia after therapy represents a recrudescence (treatment failure) or new infection. The use of capillary instead of agarose gel electrophoresis for genotyping offers technical advantages, but it is unclear whether capillary electrophoresis will result in improved classification of anti-malarial treatment...

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Identifiers

PMID: 20074380
DOI: 10.1186/1475-2875-9-19
PMCID: PMC2817701

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