Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-Cell Dissection of the Multiomic Landscape of High-Grade Serous Ovarian Cancer

15 Aug 2022

Abstract excerpt

High-grade serous cancer (HGSC) is the most common subtype of ovarian cancer. HGSC is highly aggressive with poor patient outcomes, and a deeper understanding of HGSC tumorigenesis could help guide future treatment development. To systematically characterize the underlying pathologic mechanisms and intratumoral heterogeneity in human HGSC, we used an optimized single-cell multiomics sequencing technology to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Connective Tissue Growth Factor Research
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35969151
DOI: 10.1158/0008-5472.can-21-3819

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-Cell Dissection of the Multiomic Landscape of High-Grade Serous Ovarian CancerPMID 35969151Read ↗

Genetic characterization of primary and metastatic high-grade serous ovarian cancer tumors reveals distinct features associated with survivalSemantic proximity Read ↗

Characterizing tumor biology and immune microenvironment in high-grade serous ovarian cancer via single-cell RNA sequencing: insights for targeted and personalized immunotherapy strategiesSemantic proximity Read ↗

Single-cell transcriptomics reveals the aggressive landscape of high-grade serous carcinoma and therapeutic targets in tumor microenvironmentSemantic proximity Read ↗

Multi-omic analysis of subtype evolution and heterogeneity in high-grade serous ovarian carcinomaSemantic proximity Read ↗

Single-Cell RNA Sequencing Reveals the Tissue Architecture in Human High-Grade Serous Ovarian CancerSemantic proximity Read ↗

Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian CarcinomaSemantic proximity Read ↗

Exploring the cellular and molecular differences between ovarian clear cell carcinoma and high-grade serous carcinoma using single-cell RNA sequencing and GEO gene expression signaturesSemantic proximity Read ↗

Deciphering ovarian cancer heterogeneity through spatial transcriptomics, single-cell profiling, and copy number variationsSemantic proximity Read ↗

Multiomic characterisation of high grade serous ovarian carcinoma enables high resolution patient stratificationSemantic proximity Read ↗

Differential DNA methylation in high-grade serous ovarian cancer (HGSOC) is associated with tumor behaviorSemantic proximity Read ↗

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling.Semantic proximity Read ↗

Single‐cell transcriptomes reveal heterogeneity of high‐grade serous ovarian carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.