Article
Solid-type adenoid cystic carcinoma of the breast, a distinct molecular entity enriched in NOTCH and CREBBP mutations.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2020
Massé Julie, Truntzer Caroline, Boidot Romain, Khalifa Emmanuel, Pérot Gaëlle, Velasco Valérie, Mayeur Laétitia, Billerey-Larmonier Claire, Blanchard Larry, Charitansky Hélène, Soubeyran Isabelle, Iggo Richard, Arnould Laurent, MacGrogan Gaëtan
Abstract excerpt
Adenoid cystic carcinoma (ACC) of the breast with a predominant solid pattern is difficult to diagnose with certainty and differentiate from more common triple-negative breast cancers (TNBCs) of basal-phenotype. To better characterize solid ACC, we performed a clinical, morphological, immunohistochemical, and molecular comparative analysis of 33 ACCs of the breast comprising 17 solid variant ACCs and 16...
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