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Article

Cyclin D1, Id1 and EMT in breast cancer

28 Sept 2011

Abstract excerpt

BACKGROUND: Cyclin D1 is a well-characterised cell cycle regulator with established oncogenic capabilities. Despite these properties, studies report contrasting links to tumour aggressiveness. It has previously been shown that silencing cyclin D1 increases the migratory capacity of MDA-MB-231 breast cancer cells with concomitant increase in 'inhibitor of differentiation 1' (ID1) gene expression. Id1 is known to...

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PMID: 21955753
DOI: 10.1186/1471-2407-11-417

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