Article
Evidence for pseudoknot formation of class I preQ1 riboswitch aptamers.
Chembiochem : a European journal of chemical biology - 4 May 2009
Rieder Ulrike, Lang Kathrin, Kreutz Christoph, Polacek Norbert, Micura Ronald
Abstract excerpt
All in a knot. The smallest riboswitch forms a pseudoknot in solution. This is demonstrated for preQ(1) class I aptamers by mutational analysis in combination with (1)H NMR-based structure probing. How pseudoknot formation mediates the mRNA response through its expression platform is now open for investigation.
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