Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effect of the COMT val(158)met polymorphism on neural correlates of semantic verbal fluency.

European archives of psychiatry and clinical neuroscience - 1 Dec 2009

Krug Axel, Markov Valentin, Sheldrick Abigail, Krach Sören, Jansen Andreas, Zerres Klaus, Eggermann Thomas, Stöcker Tony, Shah N Jon, Kircher Tilo

Abstract excerpt

Variation in the val(158)met polymorphism of the COMT gene has been found to be associated with cognitive performance. In functional neuroimaging studies, this dysfunction has been linked to signal changes in prefrontal areas. Given the complex modulation and functional heterogeneity of frontal lobe systems, further specification of COMT gene-related phenotypes differing in prefrontally mediated cognitive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Mapping
Share to Catechol O-Methyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Executive Function

Share to Image Processing, Computer-Assisted

Share to Methionine

Share to Semantics

Share to Valine

Share to Verbal Behavior

Source

Identifiers

PMID: 19381707
DOI: 10.1007/s00406-009-0010-8

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effect of the COMT val(158)met polymorphism on neural correlates of semantic verbal fluency.PMID 19381707Read ↗

Gender effects of the COMT Val 158 Met genotype on verbal fluency in healthy adults.Semantic proximity Read ↗

Effects of COMT polymorphisms on brain function and behavior in health and disease.Semantic proximity Read ↗

COMT genotype and its role on hippocampal-prefrontal regions in declarative memory.Semantic proximity Read ↗

Opposite effects of catechol-O-methyltransferase Val158Met on cortical function in healthy subjects and patients with schizophrenia.Semantic proximity Read ↗

The functional COMT polymorphism, Val158Met, is associated with logical memory and the personality trait intellect/imagination in a cohort of healthy 79 year oldsSemantic proximity Read ↗

COMT Val158Met polymorphism in relation to activation and de-activation in the prefrontal cortex: A study in patients with schizophrenia and healthy subjects.Semantic proximity Read ↗

Impact of the COMT Val108/158 Met and DAT genotypes on prefrontal function in healthy subjects.Semantic proximity Read ↗

Interaction of COMT (Val(108/158)Met) genotype and olanzapine treatment on prefrontal cortical function in patients with schizophrenia.Semantic proximity Read ↗

COMT val158met genotype affects recruitment of neural mechanisms supporting fluid intelligence.Semantic proximity Read ↗

Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia.Semantic proximity Read ↗

COMT val108/158met genotype, cognitive function, and cognitive improvement with clozapine in schizophrenia.Semantic proximity Read ↗

COMT Val158Met Genotype and Individual Differences in Executive Function in Healthy Adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.