Article
Spontaneous lung metastases in a human lung tumor xenograft: a new experimental model.
Journal of cancer research and clinical oncology - 1 Jan 1996
Corti C, Pratesi G, DeCesare M, Pellegrini R, Giardini R, Supino R, Zunino F
Abstract excerpt
The cell line NIH-H460, derived from a human large-cell carcinoma of the lung, because metastatic in the lung of athymic mice after S.C. injection. Using serial S.C. passages of the lung metastasis, a cell line was selected, H460M, which was characterized by an increased metastatic potential comp...
Topics
- Animals
- Carcinoma, Large Cell
- Carcinoma, Non-Small-Cell Lung
- Cell Division
- Cell Membrane
- Cell Movement
- Disease Models, Animal
- Humans
- Injections, Subcutaneous
- Lung Neoplasms
- Mice
- Mice, Nude
- Neoplasm Invasiveness
- Phenotype
- Receptors, Cell Surface
- Transplantation, Heterologous
- Tumor Cells, Cultured