Article
Spontaneous lung metastases in a human lung tumor xenograft: a new experimental model.
Journal of cancer research and clinical oncology - 1 Jan 1996
Corti C, Pratesi G, DeCesare M, Pellegrini R, Giardini R, Supino R, Zunino F
Abstract excerpt
The cell line NIH-H460, derived from a human large-cell carcinoma of the lung, because metastatic in the lung of athymic mice after S.C. injection. Using serial S.C. passages of the lung metastasis, a cell line was selected, H460M, which was characterized by an increased metastatic potential compared to the parental cells after s.c. (Spontaneous metastases) or i.v. injection (experimental metastases). For the...
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