Article
A new Mr 55,000 surface protein implicated in melanoma progression: association with a metastatic phenotype.
Cancer research - 15 Oct 2000
Boukerche H, Baril P, Tabone E, Bérard F, Sanhadji K, Balme B, Wolf F, Perrot H, Thomas L
Abstract excerpt
Emergence of the invasive phenotype is a key event in the progression of human melanoma from benign proliferative lesions to malignant lesions. Recently we successfully selected in vivo from a poorly metastatic M4Beu. human melanoma cell line two variants (7GP and T1P26) that generate a higher frequency of spontaneous metastases to the lungs into immune-suppressed neonatal rats. Both cell lines showed no...
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