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Article

The Therapeutic Potential of the Wnt Signaling Pathway in Bone Disorders

1 Jan 2011

Abstract excerpt

The Wnt pathway plays a critical role in development and differentiation of many tissues, such as the gut, hair follicles, and bone. Increasing evidence indicates that Wnts may function as key regulators in osteogenic differentiation of mesenchymal stem cells and bone formation. Conversely, aberrant Wnt signaling is associated with many osteogenic pathologies. For example, genetic alterations in the Wnt signaling...

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Share to Bone health and treatments
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Share to Wnt/β-catenin signaling in development and cancer

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PMID: 20825362
DOI: 10.2174/1874-470211104010014

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