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Article

Induction of type 2 T helper cell allergen tolerance by IL-10-differentiated regulatory dendritic cells.

American journal of respiratory cell and molecular biology - 1 Feb 2010

Li Xiuling, Yang Aimei, Huang Hui, Zhang Xiaobei, Town Jennifer, Davis Beth, Cockcroft Don W, Gordon John R

Abstract excerpt

In mouse models of asthma, therapeutic use of allergen-presenting IL-10-differentiated dendritic cells (DCs) can abrogate airway hyperresponsiveness, and reduce other asthma-related responses to near background. Analogous human DCs can suppress human T cell responses in vitro, but the operative mechanisms are poorly defined. We investigated the ability of IL-10-treated human DCs to induce tolerance among...

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Source

Identifiers

PMID: 19372244
DOI: 10.1165/rcmb.2009-0023OC

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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