Article
Regulation of allergic airway inflammation by adoptive transfer of CD4+ T cells preferentially producing IL-10.
European journal of pharmacology - 5 Oct 2017
Matsuda Masaya, Doi Kana, Tsutsumi Tatsuya, Fujii Shinya, Kishima Maki, Nishimura Kazuma, Kuroda Ikue, Tanahashi Yu, Yuasa Rino, Kinjo Toshihiko, Kuramoto Nobuyuki, Mizutani Nobuaki, Nabe Takeshi
Abstract excerpt
Anti-inflammatory pharmacotherapy for asthma has mainly depended on the inhalation of glucocorticoids, which non-specifically suppress immune responses. If the anti-inflammatory cytokine interleukin (IL)-10 can be induced by a specific antigen, asthmatic airway inflammation could be suppressed when individuals are exposed to the antigen. The purpose of this study was to develop cellular immunotherapeutics for...
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