Article
Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins.
Nature - 26 Apr 1990
Jantzen H M, Admon A, Bell S P, Tjian R
Abstract excerpt
The eukaryotic upstream binding factor (UBF), recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the species-specific factor, SL1. Isolation of complementary DNA clones and sequence analysis reveals similaritie...
Topics
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Cell Nucleolus
- Cloning, Molecular
- DNA
- DNA-Binding Proteins
- High Mobility Group Proteins
- Humans
- Molecular Sequence Data
- Molecular Weight
- Mutation
- Pol1 Transcription Initiation Complex Proteins
- Promoter Regions, Genetic
- RNA Polymerase I
- RNA, Ribosomal
- Sequence Homology, Nucleic Acid
- Transcription Factors