Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis.

doi:10.1073/pnas.96.2.715

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Article

Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 19 Jan 1999

Tan M W, Mahajan-Miklos S, Ausubel F M

Abstract excerpt

We show that a single clinical isolate of the human opportunistic pathogen Pseudomonas aeruginosa (strain PA14), which previously was shown to be pathogenic in mice and plants, also kills Caenorhabditis elegans. The rate of PA14-mediated killing of C. elegans depends on the composition of the aga...

Topics

Animals
Caenorhabditis elegans
Cell Division
Culture Media
Intestines
Microscopy, Fluorescence
Mutation
Pseudomonas aeruginosa
Virulence

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