Article
HLA DRw8 and complement C4 deficiency as risk factors in primary biliary cirrhosis.
Gastroenterology - 1 Nov 1991
Manns M P, Bremm A, Schneider P M, Notghi A, Gerken G, Prager-Eberle M, Stradmann-Bellinghausen B, Meyer zum Büschenfelde K H, Rittner C
Abstract excerpt
HLA class I, II, and III alleles were investigated in 25 consecutive unrelated German patients with primary biliary cirrhosis and in two families with two primary biliary cirrhosis patients in each. In primary biliary cirrhosis patients, HLA class I antigens did not differ significantly from in health controls. For HLA class II antigens, a highly significant increase of HLA DRw8 was found in patients with primary...
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