Human leukocyte antigen in primary biliary cirrhosis: an old story now reviving.

doi:10.1002/hep.24414

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Article

Human leukocyte antigen in primary biliary cirrhosis: an old story now reviving.

Hepatology (Baltimore, Md.) - 1 Aug 2011

Invernizzi Pietro

Abstract excerpt

Primary biliary cirrhosis (PBC) is an autoimmune biliary disease characterized by injury of small and medium size bile ducts, eventually leading to liver cirrhosis and death. Although the causes remain enigmatic, recent evidence has strengthened the importance of genetic factors in determining the susceptibility to the disease. Besides the strong heritability suggested by familial occurrence and monozygotic twins...

Topics

Animals
Genetic Predisposition to Disease
HLA Antigens
Humans
Liver Cirrhosis, Biliary

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Identifiers

PMID: 21563204
DOI: 10.1002/hep.24414
PMCID: PMC3145017

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