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Article

Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer.

British journal of cancer - 19 May 2009

Chang-Claude J, Ambrosone C B, Lilla C, Kropp S, Helmbold I, von Fournier D, Haase W, Sautter-Bihl M-L, Wenz F, Schmezer P, Popanda O

Abstract excerpt

Breast-conserving surgery followed by radiotherapy is effective in reducing recurrence; however, telangiectasia and fibrosis can occur as late skin side effects. As radiotherapy acts through producing DNA damage, we investigated whether genetic variation in DNA repair and damage response confers...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19367277
DOI: 10.1038/sj.bjc.6605036
PMCID: PMC2696768

Genes

APEX1
XRCC1
XRCC2
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19367277-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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