[A study on the relation between the apolipoprotein E promoter -427C/T polymorphism and Alzheimer's disease].

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Article

[A study on the relation between the apolipoprotein E promoter -427C/T polymorphism and Alzheimer's disease].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2003

Tang Guo-mei, Zhang Ming-yuan, Jiang San-duo, Qian Yi-ping, Wang Dong-xiang

Abstract excerpt

OBJECTIVE: To determine the relation between the apolipoprotein E(apoE) promoter -427C/T polymorphism and Alzheimer's disease (AD) in a Chinese Han population in Shanghai. METHODS: The apoE promoter -427C/T polymorphism in 104 AD cases and 110 healthy subjects was detected using polymerase chain reaction method and restriction fragment length polymorphism genotyping technique. The differences in polymorphic...

Topics

Aged
Aged, 80 and over
Alzheimer Disease
Apolipoproteins E
Asian People
China
Female
Gene Frequency
Genotype
Humans
Male
Middle Aged
Polymorphism, Genetic
Promoter Regions, Genetic

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Open in PubMed

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PMID: 12778455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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