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Article

Reaction cycle of Thermotoga maritima copper ATPase and conformational characterization of catalytically deficient mutants.

Biochemistry - 9 Jun 2009

Hatori Yuta, Lewis David, Toyoshima Chikashi, Inesi Giuseppe

Abstract excerpt

Copper transport ATPases sustain important roles in homeostasis of heavy metals and delivery of copper to metalloenzymes. The copper transport ATPase from Thermotoga maritima (CopA) provides a useful system for mechanistic studies, due to its heterologous expression and stability. Its sequence comprises 726 amino acids, including the N-terminal metal binding domain (NMBD), three catalytic domains (A, N, and P),...

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Identifiers

PMID: 19364131
DOI: 10.1021/bi900338n
PMCID: PMC2756213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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