Article
Functional significance of CD14 promoter polymorphisms and their clinical relevance in a Chinese Han population.
Critical care medicine - 1 Aug 2008
Gu Wei, Dong Hong, Jiang Dong-Po, Zhou Jian, Du Ding-Yuan, Gao Jin-Mou, Yao Yuan-Zhang, Zhang Lian-Yang, Wen Ai-Qing, Liu Qing, Wang Zheng-Guo, Jiang Jian-Xin
Abstract excerpt
OBJECTIVE: Several polymorphisms in the CD14 promoter have been reported to be associated with various inflammatory diseases. However, conflicting results have been shown in association studies in different populations. This study aimed to investigate the possible functional significance of both the G-1145A and T-159C polymorphisms in the CD14 promoter and their association with organ dysfunction and sepsis in...
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