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Article

Polymorphisms in the CD14 gene associated with pulmonary function in farmers.

American journal of respiratory and critical care medicine - 1 Apr 2005

LeVan Tricia D, Von Essen Susanna, Romberger Debra J, Lambert G Patrick, Martinez Fernando D, Vasquez Monica M, Merchant James A

Abstract excerpt

RATIONALE AND OBJECTIVES: Farmers experience airway obstruction, which may be attributable in part to endotoxin inhalation. CD14 is a receptor for endotoxin. MATERIALS AND METHODS: Based on our findings of increased circulating CD14 associated with the CD14/-159 T allele, we hypothesized that carriers of this allele would have decreased lung function among endotoxin-exposed individuals. CD14/-159TT farmers (n =...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15591473
DOI: 10.1164/rccm.200404-530OC

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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