Article
Gene by environment interaction: the -159C/T polymorphism in the promoter region of the CD14 gene modifies the effect of alcohol consumption on serum IgE levels.
Alcoholism, clinical and experimental research - 1 Jan 2006
Campos Joaquin, Gude Francisco, Quinteiro Celsa, Vidal Carmen, Gonzalez-Quintela Arturo
Abstract excerpt
BACKGROUND: Serum IgE is increased in heavy drinkers. Endotoxin mediates most of the immunological alterations associated with heavy drinking. The -159C/T polymorphism in the promoter region of the gene encoding CD14 (an endotoxin receptor) is associated with serum IgE levels in different populat...
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