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Article

Gene by environment interaction: the -159C/T polymorphism in the promoter region of the CD14 gene modifies the effect of alcohol consumption on serum IgE levels.

Alcoholism, clinical and experimental research - 1 Jan 2006

Campos Joaquin, Gude Francisco, Quinteiro Celsa, Vidal Carmen, Gonzalez-Quintela Arturo

Abstract excerpt

BACKGROUND: Serum IgE is increased in heavy drinkers. Endotoxin mediates most of the immunological alterations associated with heavy drinking. The -159C/T polymorphism in the promoter region of the gene encoding CD14 (an endotoxin receptor) is associated with serum IgE levels in different populations. AIM: To investigate the possible interaction between alcohol intake and the -159C/T polymorphism in the promoter...

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Identifiers

PMID: 16433727
DOI: 10.1111/j.1530-0277.2006.00007.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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