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Article

Insights into how RNase R degrades structured RNA: analysis of the nuclease domain.

Journal of molecular biology - 3 Apr 2009

Vincent Helen A, Deutscher Murray P

Abstract excerpt

RNase R readily degrades highly structured RNA, whereas its paralogue, RNase II, is unable to do so. Furthermore, the nuclease domain of RNase R, devoid of all canonical RNA-binding domains, is sufficient for this activity. RNase R also binds RNA more tightly within its catalytic channel than does RNase II, which is thought to be important for its unique catalytic properties. To investigate this idea further,...

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Identifiers

PMID: 19361424
DOI: 10.1016/j.jmb.2009.01.068
PMCID: PMC2786168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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