Article
[Identification of low-penetrance alleles associated with colon cancer risk].
Medecine sciences : M/S - 1 Mar 2009
Houlston Richard
Abstract excerpt
Colorectal cancer affects over 500,000 individuals yearly. Much of the benefit of colorectal cancer screening has been attributed to detection and removal of adenomatous polyps, highlighting the importance of colorectal polyps as targets for intervention and as biomarkers for colorectal cancer risk. Positive familial history (first or second degree relative) for colorectal carcinoma can be found in approximately...
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