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Article

Genome-wide association studies and colorectal cancer.

Surgical oncology clinics of North America - 1 Oct 2009

Le Marchand Loïc

Abstract excerpt

Genome-wide association studies (GWAS) provide a powerful new approach to identify common, low-penetrance susceptibility loci without prior knowledge of biologic function. Results from three GWAS conducted in populations of European ancestry are available for colorectal cancer (CRC). These studies have identified 11 disease loci that, for the majority, were not previously suspected to be related to CRC. The...

Topics

Colorectal Neoplasms
Genetic Predisposition to Disease
Genome-Wide Association Study
Humans

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19793573
DOI: 10.1016/j.soc.2009.07.004
PMCID: PMC2756243

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