Article
Genome-wide association studies and colorectal cancer.
Surgical oncology clinics of North America - 1 Oct 2009
Le Marchand Loïc
Abstract excerpt
Genome-wide association studies (GWAS) provide a powerful new approach to identify common, low-penetrance susceptibility loci without prior knowledge of biologic function. Results from three GWAS conducted in populations of European ancestry are available for colorectal cancer (CRC). These studies have identified 11 disease loci that, for the majority, were not previously suspected to be related to CRC. The...
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