Article
CASP-9: A susceptibility locus for multiple sclerosis in Italy.
Journal of neuroimmunology - 29 May 2009
Andreoli V, Trecroci F, La Russa A, Valentino P, Condino F, Latorre V, Nisticò R, Pirritano D, Del Giudice F, Canino M, Cittadella R, Quattrone A
Abstract excerpt
Caspase-9 is a primary effector CASP that executes programmed cell death, which plays an important role in the development of multiple sclerosis (MS). Polymorphisms in the CASP-9 gene may influence its activity, thereby modulating the susceptibility to MS. To test this hypothesis, we evaluated a SNP in the CASP-9 gene in a set of Italian patients from Southern Italy and healthy control subjects. Our results...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.