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Article

Interaction between variants of two glycosyltransferase genes in IgA nephropathy.

Kidney international - 1 Jul 2009

Zhu Li, Tang Wanwan, Li Guisen, Lv Jicheng, Ding Jiaxiang, Yu Lei, Zhao Minghui, Li Yanda, Zhang Xuegong, Shen Yan, Zhang Hong, Wang Haiyan

Abstract excerpt

Increasing evidence points to the importance of aberrant O-glycosylated immunoglobulin A1 (IgA1) in the pathogenesis of IgA nephropathy (IgAN), a disease widely considered to be a polygenic disorder. We earlier found that haplotypes in two key glycosyltransferase genes, C1GALT1 and ST6GALNAC2, were associated with susceptibility to IgAN. Here we measured the genetic interaction of variants in C1GALT1 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19357720
DOI: 10.1038/ki.2009.99

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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