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The genetics and epidemiology of<i>N-</i>and<i>O-</i>IgA glycomics

2024-01-07

Abstract excerpt

Immunoglobulin (Ig) glycosylation modulates the immune response, and plays a critical role in ageing and diseases. Studies have mainly focused on IgG glycosylation, and little is known about the genetics and epidemiology of IgA glycosylation. Here, we generated, using a novel LC-MS method, the first large-scale IgA glycomics dataset in serum from 2,423 twins, encompassing 71 N- and O- glycan species. We showed tha...

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Literature Corpus work
c8c27956-9247-52f2-b7fd-e2376ecd5fab
DOI
10.1101/2024.01.05.24300885
Open publication

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The genetics and epidemiology of<i>N-</i>and<i>O-</i>IgA glycomicsDOI 10.1101/2024.01.05.24300885
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