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Article

Smad2 and 3 transcription factors control muscle mass in adulthood.

American journal of physiology. Cell physiology - 1 Jun 2009

Sartori Roberta, Milan Giulia, Patron Maria, Mammucari Cristina, Blaauw Bert, Abraham Reimar, Sandri Marco

Abstract excerpt

Loss of muscle mass occurs in a variety of diseases, including cancer, chronic heart failure, aquired immunodeficiency syndrome, diabetes, and renal failure, often aggravating pathological progression. Preventing muscle wasting by promoting muscle growth has been proposed as a possible therapeutic approach. Myostatin is an important negative modulator of muscle growth during myogenesis, and myostatin inhibitors...

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Identifiers

PMID: 19357234
DOI: 10.1152/ajpcell.00104.2009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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