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Article

Role of TGF-β signaling in inherited and acquired myopathies

1 Jan 2011

Abstract excerpt

The transforming growth factor-beta (TGF-β) superfamily consists of a variety of cytokines expressed in many different cell types including skeletal muscle. Members of this superfamily that are of particular importance in skeletal muscle are TGF-β1, mitogen-activated protein kinases (MAPKs), and myostatin. These signaling molecules play important roles in skeletal muscle homeostasis and in a variety of inherited...

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Share to Cardiomyopathy and Myosin Studies
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PMID: 21798096
DOI: 10.1186/2044-5040-1-19

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