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Article

Association of MICA-TM and MICB C1_2_A microsatellite polymorphisms with tumor progression in patients with colorectal cancer.

Journal of clinical immunology - 1 Jul 2009

Kopp R, Glas J, Lau-Werner U, Albert E D, Weiss E H

Abstract excerpt

PURPOSE: The major histocompatibility complex class I related A (MICA) and MICB molecules are ligands of NKG2D receptors on natural killer cells, gamma/delta T cells, and CD8ass T cells that mediate host antitumor immune response. The role of MICA-TM and MICB C1_2_A alleles in patients with colorectal cancer has not yet been investigated. METHODS: We have analyzed the MICA-TM and MICB C1_2_A polymorphisms in...

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Identifiers

PMID: 19353249
DOI: 10.1007/s10875-009-9288-6
PMCID: PMC2701994

Genes

MICA
MICB
KRAS

Provenance

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Association of MICA-TM and MICB C1_2_A microsatellite polymorphisms with tumor progression in patients with colorectal cancer.PMID 19353249Read ↗

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