Article
Heritability of age of onset of psychosis in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2010
Hare Elizabeth, Glahn David C, Dassori Albana, Raventos Henriette, Nicolini Humberto, Ontiveros Alfonso, Medina Rolando, Mendoza Rick, Jerez Alvaro, Muñoz Rodrigo, Almasy Laura, Escamilla Michael A
Abstract excerpt
Schizophrenia is a genetically complex illness with heterogeneous clinical presentation, including variable age of onset. In this study, the heritability, or proportion of variation in age of onset of psychotic symptoms due to genetic factors, was estimated using a maximum likelihood method. The subjects were 717 members of families with more than one member affected with schizophrenia from Mexican and Central...
Topics
- Adult
- Age of Onset
- Female
- Humans
- Male
- Polymorphism, Single Nucleotide
- Psychotic Disorders
- Schizophrenic Psychology