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Article

N-methyl-D-aspartate 2b receptor subtype (NR2B) promoter methylation in patients during alcohol withdrawal.

Journal of neural transmission (Vienna, Austria : 1996) - 1 May 2009

Biermann Teresa, Reulbach Udo, Lenz Bernd, Frieling Helge, Muschler Marc, Hillemacher Thomas, Kornhuber Johannes, Bleich Stefan

Abstract excerpt

NMDA receptors and especially the NR2B receptor subtype play a crucial role during chronic ethanol consumption and alcohol withdrawal. Therefore, the NR2B receptor subtype expression in peripheral blood cells of 32 male patients suffering from alcohol dependency were assessed through quantitative RT-PCR and to explore regulating epigenetic mechanisms, a methylation analysis was conducted using bisulfite...

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Share to Alcoholism
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Epigenesis, Genetic

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Share to Receptors, N-Methyl-D-Aspartate

Share to Substance Withdrawal Syndrome

Source

Identifiers

PMID: 19350219
DOI: 10.1007/s00702-009-0212-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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