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Article

GRIN1 locus may modify the susceptibility to seizures during alcohol withdrawal.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Feb 2005

Rujescu D, Soyka M, Dahmen N, Preuss U, Hartmann A M, Giegling I, Koller G, Bondy B, Möller H-J, Szegedi A

Abstract excerpt

N-Methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily, are generally inhibited by alcohol. The expression and alternative splicing of the obligatory NR1 subunit is altered by alcohol exposure, emphasizing the involvement of the NR1 subunit, which is coded by the GRIN1 gene, in alcohol-mediated effects. We performed an association study in patients with alcohol dependence...

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Source

Identifiers

PMID: 15635650
DOI: 10.1002/ajmg.b.30112

Genes

GRIN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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