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Article

Cortical NMDA receptor expression in human chronic alcoholism: influence of the TaqIA allele of ANKK1.

Neurochemical research - 1 Oct 2009

Ridge Justin P, Dodd Peter R

Abstract excerpt

Real-time RT-PCR normalized to GAPDH was used to assay N-methyl-D-aspartate (NMDA) receptor NR1, NR2A and NR2B subunit mRNA in human autopsy cortex tissue from chronic alcoholics with and without comorbid cirrhosis of the liver and matched controls. Subunit expression was influenced by the subject's genotype. The TaqIA polymorphism selectively modulated NMDA receptor mean transcript expression in...

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Share to Alcoholism
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Enzymologic

Share to Polymorphism, Genetic

Share to Protein Serine-Threonine Kinases

Share to Receptors, N-Methyl-D-Aspartate

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Source

Identifiers

PMID: 19283474
DOI: 10.1007/s11064-009-9941-8

Genes

GAPDH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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