Article
The three domains of the mitochondrial outer membrane protein Mim1 have discrete functions in assembly of the TOM complex.
FEBS letters - 6 May 2009
Lueder Franziska, Lithgow Trevor
Abstract excerpt
The assembly of mitochondrial outer membrane proteins is an essential process, mediated by the SAM complex and a set of additional protein modules. We show that one of these, Mim1, is anchored in the outer membrane with its N-terminus exposed to the cytosol and its C-terminus in the mitochondrial intermembrane space. Using an in vitro assay to measure the multi-step pathway for assembly of Tom40 into the TOM...
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