Article
Precursor oxidation by Mia40 and Erv1 promotes vectorial transport of proteins into the mitochondrial intermembrane space.
Molecular biology of the cell - 1 Jan 2008
Müller Judith M, Milenkovic Dusanka, Guiard Bernard, Pfanner Nikolaus, Chacinska Agnieszka
Abstract excerpt
The mitochondrial intermembrane space contains chaperone complexes that guide hydrophobic precursor proteins through this aqueous compartment. The chaperones consist of hetero-oligomeric complexes of small Tim proteins with conserved cysteine residues. The precursors of small Tim proteins are syn...
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