Article
Mitochondrial protein import: Mia40 facilitates Tim22 translocation into the inner membrane of mitochondria.
Molecular biology of the cell - 1 Mar 2013
Wrobel Lidia, Trojanowska Agata, Sztolsztener Malgorzata E, Chacinska Agnieszka
Abstract excerpt
The mitochondrial intermembrane space assembly (MIA) pathway is generally considered to be dedicated to the redox-dependent import and biogenesis of proteins localized to the intermembrane space of mitochondria. The oxidoreductase Mia40 is a central component of the pathway responsible for the transfer of disulfide bonds to intermembrane space precursor proteins, causing their oxidative folding. Here we present...
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