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Article

Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins.

The EMBO journal - 1 Oct 2004

Chacinska Agnieszka, Pfannschmidt Sylvia, Wiedemann Nils, Kozjak Vera, Sanjuán Szklarz Luiza K, Schulze-Specking Agnes, Truscott Kaye N, Guiard Bernard, Meisinger Chris, Pfanner Nikolaus

Abstract excerpt

Mitochondria import nuclear-encoded precursor proteins to four different subcompartments. Specific import machineries have been identified that direct the precursor proteins to the mitochondrial outer membrane, inner membrane or matrix, respectively. However, a machinery dedicated to the import of mitochondrial intermembrane space (IMS) proteins has not been found so far. We have identified the essential IMS...

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Identifiers

PMID: 15359280
DOI: 10.1038/sj.emboj.7600389
PMCID: PMC522791

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Source receipt: pubmed, retrieved 7 Sept 2026.

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