Article
Alternative function for the mitochondrial SAM complex in biogenesis of alpha-helical TOM proteins.
The Journal of cell biology - 3 Dec 2007
Stojanovski Diana, Guiard Bernard, Kozjak-Pavlovic Vera, Pfanner Nikolaus, Meisinger Chris
Abstract excerpt
The mitochondrial outer membrane contains two preprotein translocases: the general translocase of outer membrane (TOM) and the beta-barrel-specific sorting and assembly machinery (SAM). TOM functions as the central entry gate for nuclear-encoded proteins. The channel-forming Tom40 is a beta-barre...
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