Article
Risk of non-Hodgkin lymphoma in association with germline variation in complement genes.
British journal of haematology - 1 Jun 2009
Cerhan James R, Novak Anne J, Fredericksen Zachary S, Wang Alice H, Liebow Mark, Call Timothy G, Dogan Ahmet, Witzig Thomas E, Ansell Stephen M, Habermann Thomas M, Kay Neil E, Slager Susan L
Abstract excerpt
Germline mutations in complement genes have been associated with susceptibility to infections and autoimmune diseases, conditions that are associated with non-Hodgkin lymphoma (NHL) risk. To test the hypothesis that common genetic variation in complement genes affect risk of NHL, we genotyped 167 single nucleotide polymorphisms (SNPs) from 31 genes in 441 NHL cases and 475 controls. Principal components (PC) and...
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